Research Papers
- Light-Driven Changes in Energy Metabolism Directly Entrain the Cyanobacterial Circadian Oscillator
- A Vision for a Biomedical Cloud (J Intern Med. 2011 Dec 5. doi: 10.1111/j.1365-2796.2011.02491)
- Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness (Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, United States of America)
- Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.
- Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data (Proc Natl Acad Sci U S A. 2011 Jul 5.)
- A user's guide to the encyclopedia of DNA elements (ENCODE). (PLoS Biol. 2011 Apr;9(4):e1001046. Epub 2011 Apr 19)
Inflammatory Bowel Disease
Eugene Chang, MD (Department of Medicine, Section of Gastroenterology) has partnered with IGSB Core Member Dion Antonopoulos, PhD (IGSB, Argonne) to sequence patient gut contents, containing thousands of different bacterial species, to determine the relationship between specific bacteria and inflammatory bowel disease.
This metagenomics project has been supported by seed funding from the Institute’s Inflammatory Bowel Disease Initiative and takes advantage of the next generation sequencing technology within the High-Throughput Genome Analysis Core (HGAC), as well as the computational expertise at Argonne.
Dionysios Antonopolis,
IGSB Core Faculty
Eugene Chang, MD
Director
Digestive Diseases Research Core Center
University of Chicago