- Professor & Chairman, Dept. of Molecular Genetics & Cell Biology, University of Chicago
Department of Molecular Genetics & Cell Biology
The University of Chicago
920 E. 58th St., CLSC 925A
Chicago, IL 60637
Phone: 773 702 5694
Fax: 773 702 5694
Our interests center on the molecular mechanisms by which signal transduction pathways are organized into specialized membrane domains. In addition to their known role in organizing receptors and downstream effectors into functional signaling complexes, such organized complexes function to integrate signaling activities from multiple pathways and to segregate simultaneous but distinct functions of a single pathway.
We study this question in Drosophila because of the utility of this system for studying the functions of individual genes via mutagenesis, and for examining the functional interactions between different genes that work together in a particular cellular or developmental process.