- Louis Block Distinguished Service Professor of Medicine & Human Genetics, The University of Chicago
- Director, Diabetes Research & Training Center, The University of Chicago
Department of Medicine
The University of Chicago
5841 S. Maryland Ave., AMB N237, MC1027
Chicago, IL 60637
Phone: (773) 702-9116
Fax: (773) 702-9237
Dr. Bell’s research focuses on the genetics of diabetes mellitus and the biology of the insulin-secreting pancreatic beta-cell. The goals of his research program are:
- To identify the genes that contribute to the development of diabetes and its complications and to determine the molecular and physiological mechanisms by which they control blood glucose levels; and
- To identify transcriptional regulatory networks responsible for the regulation of gene expession in pancreatic beta-cell using genome-scale approaches.
He and his colleagues are using various genetic approaches to map and identify the genes that affect development of type 2 diabetes mellitus as well as diabetic complications. They carry out studies in both humans and mouse models to determine the mechanisms by which the diabetes genes they identify affect blood glucose levels. Their studies of pancreatic beta-cells are focused on understanding the transcriptional regulatory networks that determine normal cell function.