David Vanderweele

- Instructor, Department of Medicine, Section of Hematology/Oncology

Contact Information

Knapp Center for Biomedical Discovery
900 East 57th Street

Phone: (773) 834-0074
Email: .(JavaScript must be enabled to view this email address)


I am a hematology-oncology fellow/postdoctoral fellow with Kevin White at the University of Chicago.  I was a graduate student with Charles Rudin in the Committee on Cancer Biology at the University of Chicago, and I completed residency in Internal Medicine at the University of Chicago Medicine.  My clinical work focuses on genitourinary malignancies, including prostate, urothelial, kidney, and testicular cancer.  In the lab I am focused on cancer genomics, primarily that of GU malignancies.  Current projects include (a) studying the evolution of solid tumors through comparison of genetic changes over time and space, and (b) identification of genetic biomarkers for use in prognosis and prediction of response to therapy.


Prostate cancer is the leading cancer diagnosis in American men, excluding skin cancer.  The natural history of prostate cancer is widely variable, and our insight into prognosis and response to therapy is guided mostly by pathology.  My project involves using sequencing data to evaluate prostate cancer progression, and to define prostate cancer subtypes.

Research Papers