Barbara Stranger

IGSB, Core Member, Fellow,
- Assistant Professor, Department of Medicine, Section of Genetic Medicine

Contact Information

Institute for Genomics and Systems Biology
The University of Chicago
900 E. 57th Street
KCBD 10134
Chicago, IL 60637

Phone: 773-702-4301
Email: .(JavaScript must be enabled to view this email address)
Website: https://aaa-uruk04.cri.uchicago.edu/profiles/display/915383

Bio

Dr. Barbara Stranger has a longstanding interest in population genetics and gene regulatory processes, and how these shape phenotypic variability. Her lab collects and analyzes multi-dimensional human genomics data, particularly transcriptome data and genetic variation data, in the context of health and disease. She had made many contributions to the field of expression QTL (eQTL) mapping in human populations, including large-scale genome-wide eQTL studies in humans, cross-tissue eQTL analysis of a single cohort, analysis of eQTLs in populations of diverse ancestry, sex-specific eQTLs in humans, and others. She has also successfully integrated eQTLs with disease, including cancer and inflammatory diseases, and published methods and resources for doing so. Current projects in her lab integrate regulatory genomics (including transcriptomics and proteomics) with human disease mapping, as well as characterizing the context-specificity of genetic and epigenetic effects on gene regulation (e.g., cell-type, sex, age).


Research Papers