Computational Recipes in Enzymology
How do rich biological behaviors arise from bi-molecular collisions? Living cells are capable of a remarkably diverse spectrum of behaviors in response to cues from their environment. These behaviors range from switch-like responses, to the ability to detect minute variations in stimulus against a uniform background, to the generation of self-sustaining oscillations. The quantitative properties of cellular behavior can often be usefully summarized by an input-output relationship (similar to a dose-response curve), allowing us to visualize the response of a system as a function of an applied stimulus.
- Profiling Reactive Metabolites via Chemical Trapping and Targeted Mass Spectrometry
- Does the brain listen to the gut?
- (Meta)genomic insights into the pathogenome of Cellulosimicrobium cellulans
- A robust adaptive denoising framework for real-time artifact removal in scalp EEG measurements
- Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx
- Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break
- Controlling the Cyanobacterial Clock by Synthetically Rewiring Metabolism
- Choosing experiments to accelerate collective discovery
- The transcriptional landscape of age in human peripheral blood
- Digital signaling decouples activation probability and population heterogeneity