Identifying Network Biomarkers and their Application to Complex Diseases


Luonan Chen, PhD


July 29, 2011, 5:00 pm – 6:00 pm




CCCC-SM “Identifying Network Biomarkers and their Application to Complex Diseases”

Submitting Unit:
University of Chicago Comprehensive Cancer Center
Type of Event: Seminar
Date of Event: Friday, July 29 2011
Start Time: 4:00 PM
End Time: 5:00 PM
Building: Knapp Center for Biomedical Discovery, Room 1103

Title of talk or presentation:
“Identifying Network Biomarkers and their Application to Complex Diseases”

Speaker’s Name and Degrees:
Dr. Luonan Chen, PhD

Speaker’s Institutional Affiliation:
Professor, Executive director, Key Laboratory of Systems Biology, Chinese Academy of Sciences, Shanghai, China

Dr. Luonan Chen is an international leader of translational bioinformatics directing the largest nationally funded Key Laboratory of Computational Biology in China. In his talk, he will describe the benefits of network modeling for biomarker discovery and characterization that can make use of the vast data sources currently available from high-throughput experimentation. Furthermore, Dr. Chen will discuss how this data can be used to examine biomolecular networks in living organisms that cannot otherwise be fully understood by merely analyzing their individual components and that require the examination of the interactions of their parts or biomolecular networks which are ultimately responsible for the organism’s form, function and pathology. Dr. Chen’s talk will address the need for new computational tools and approaches for revealing essential biological mechanisms and thus “network biomarkers” and their specific relationship, relevance and applications for complex diseases.

Luonan Chen received the M.E. and Ph.D. degrees in the electrical engineering, from Tohoku University, Sendai, Japan, in 1988 and 1991, respectively. From 1997, he was an associate professor of the Osaka Sangyo University, Osaka, Japan, and then a full Professor. Since 2010, he has been the excutive director at Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. He was the founding director of Institute of Systems Biology, Shanghai University, and from 2010 he has also been a research professor in Institute of Industrial Science, The University of Tokyo, Japan. He serves as Chair of Technical Committee of Systems Biology at IEEE SMC Society, and President of Computational Systems Biology of ORS China. His fields of interest are systems biology, bioinformatics and nonlinear dynamics. He serves as editor or editorial board member for many systems biology related journals, e.g. BMC Systems Biology, IEEE/ACM Trans. on Computational Biology and Bioinformatics, IET Systems Biology, Journal of Theorretical Biology, Mathematical Biosciences, Neural Processing Letters, Frontier in Systems Physiology, Int. J. of Systems and Synthetic Biology, and J. of Systems Science and Complexity. In recent five years, he published over 100 journal papers and two monographs on the area of systems biology.

Webpage URL (if any):

Contact Name:
Dr. Xinan Yang

Contact Email:

Contact Phone:

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