Evolution of DNA methylation in Animal Genomes


Soojin Yi, Ph.D., Associate Professor


October 17, 2011, 4:30 pm – 5:30 pm


BSLC 008


ECEV-SM Evolution of DNA methylation in Animal Genomes

Submitting Unit:Ecology & Evolution
Type of Event: Seminar
Date of Event: Monday, October 17 2011
Start Time: 3:30 PM
End Time: 4:45 PM
Building: BSLC Room 008

Title of talk or presentation:
Evolution of DNA methylation in Animal Genomes

Speaker’s Name and Degrees:
Soojin Yi, Ph.D., Associate Professor

Speaker’s Institutional Affiliation:
School of Biology, Georgia Institute of Technology, Atlanta, GA

Soojin Yi, Ph.D. - “Evolution of DNA methylation in Animal Genomes”


DNA methylation is a phylogenetically widespread epigenetic mechanism known to be crucial in regulation and development. In this talk I will summarize recent advances on understanding evolutionary trajectories of DNA methylation in animal genomes. Interestingly, patterns of genomic DNA methylation exhibit considerable variation among taxa. For example, vertebrate genomes tend to show extensive levels of DNA methylation. In contrast, invertebrate genomes often display reduced or minimal levels of methylation. This variation in genome methylation patterns is of great interest, as it suggests that the role of DNA methylation is not strictly conserved among species. In this talk, I will discuss a few recent studies from my laboratory investigating evolution of DNA methylation in animals. In particular we found evidence that DNA methylation plays a fundamental role in caste-specific gene expression in honey bee Apis mellifera. DNA methylation is implicated in the origin of CpG islands in vertebrate genomes, and may underlie species-specific patterns of gene expression.

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Noami Perez

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