Postdoctoral position on spatially resolved single-cell analysis from tissue

Applications are invited for an immediate opening at the Systems Biology and Bioengineering Group led by Professor Savas Tay, at the Institute for Molecular Engineering, University of Chicago (

Our group develops single-cell analysis methods and microfluidic systems to improve measurement functionality, accuracy, and throughput and applies these tools to problems in signaling, immunity and cellular information processing. We are particularly interested in multiplexed proteomic and transcriptomic methods at the single-cell level, with applications to intact tissue. In this project, we will develop single cell sequencing and single-cell proteomics methods where the spatial position of every cell in the tissue is recorded along with the measurement of its genome, transcriptome, and proteome. Such a measurement capability will allow us to discover new cell types and functional states, create a Human Cell Atlas, and broadly impact a range of fields in Systems Biology and Medicine.

Applications from a range of backgrounds including Engineering, Chemistry, Physics, and Biology are invited. Desired skills include cell culture, basic biochemistry, microscopy, image processing, and programming. Dealing with tissue sections will be necessary. Experience with sequencing, microfluidics, cloning, and modeling are a plus. Our laboratory is affiliated with the Institute for Molecular Engineering ( and Institute for Genomics and Systems Biology ( Highly motivated candidates should send an application package with research interests, full CV with experimental and computational skills listed in detail, names and contact information of 3 references to Savas Tay ( Applications should be submitted beginning August 10, 2017, and applications will be considered until the position is filled.

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